Test ID: ZH121
CPT code: 81332, 82103
LOINC:
Specimen Type: Red or SST AND Lav (EDTA)
Frequency: 6 – 12 days
Instructions: 3mL serum (1.5mL in each of 2 tubes) from Red or SST refrigerated AND 7mL whole blood from Lav(EDTA) ambient. Min 1.2 mL serum AND 3 mL WB
Text: AAT may be elevated into normal range in heterozygous-deficient patients during infection, pregnancy, estrogen or steroid therapy, cancer, & during postoperative period. Homozygous-deficient patients will not show such elevation. In normals, pregnancy & contraceptive medications may elevate levels. Levels are normally low at birth but will rise soon.
Methodology: A1AT Quant:Immunologic; genotype:multiplex allele-specific polymerase chain reaction and gel electrophoresis;phenotype: isoelectric focusing