Test ID: ZH125
Component(s): Z5034 Alpha-Thalassemia LOINC: 21687-9
CPT code: 81257
LOINC:
Specimen Type: Lav(EDTA),Yel(ACD),sterile conical,OR 2confluent T25 flasks for fetal testing
Frequency: 9 – 12 days within 10 days. Will adjust according to volume
Instructions: 10mL amnio fld,20mgCVS or 7mL WB-Lav(EDTA),Yel(ACD),sterile conical,OR 2 confluent T25Flasks for fetal, Ambient. Min 3mLWB, 5mLAmnio OR 10mgCVS
Text: α-Thalassemia is the most common inherited disorder of hemoglobin synthesis in the world. α-Thalassemia can occur in all ethnic groups but is more common in those of Southeast Asian descent. Hemoglobinopathy screening is recommended for those of African, Southeast Asian, and Mediterranean descent.
Methodology: Polymerase chain reaction (PCR) and multiplex ligation probe amplification (MLPA)