Test ID: ZH219
CPT code:
LOINC:
Specimen Type: CSF
Frequency: Setup: Varies; Analytic time:3 days if negative/5 days if positive
Instructions: 4.0mL CSF in sterile vial. Refrigerated.
Text: Investigating new onset cryptogenic epilepsy with incomplete seizure control and duration of less than 2 years
Investigating new onset cryptogenic epilepsy plus 1 or more of the following accompaniments:
-Psychiatric accompaniments (psychosis, hallucinations)
-Movement disorder (myoclonus, tremor, dyskinesias)
-Headache
-Cognitive impairment/encephalopathy
-Autoimmune stigmata (personal history or family history or signs of diabetes mellitus, thyroid disorder, vitiligo, premature graying of hair,myasthenia gravis, rheumatoid arthritis, systemic lupus erythematosus, idiopathic adrenocortical insufficiency), or multiple sclerosis
-History of cancer
-Smoking history (20+ pack years) or other cancer risk factors
-Investigating seizures occurring within the context of a subacute multifocal neurological disorder without obvious cause, especially in a patient with past or family history of cancer
Methodology: Indirect Immunofluorescence Assay (IFA), Radioimmunoassay (RIA), Western lot (WB), Cell Binding Assay (CBA), NMO-IgG Fluorescence-Activated Cell