Test ID: Z0458
CPT code: 83921
LOINC: 13964-2
Specimen Type: Red, SST OR green-top (heparin) tube
Frequency: 3 – 6 days six working days after setup by performing lab.
Instructions: 2 mL Serum or Plasma from Red, SST OR green-top (heparin) tube, Refrigerated, Separate within one hour. Min 0.6 mL.
Text: Serum methylmalonic acid is used to evaluate individuals with signs & symptoms associated with vitamin B12 deficiency or congenital methylmalonic academia. MMA measurement is used as a diagnostic test for vitamin B12 deficiency. Follow-up measurement of MMA can be of value in assessing the effectiveness of vitamin B12 supplementation of deficient patients.
Methodology: Liquid chromatography/tandem mass spectrometry (LC/MS-MS)